Niosomes as Transdermal Drug Delivery System

Niosomes – Vesicular Drug Delivery System

At present days drugs are formulated by using different novel drug delivery system (NDDS) which are used for targeting drugs to different organ systems and for controlled /sustained release of drug from the dosage forms. The NDDS can be used to overcome many disadvantages of conventional dosage forms like poor bioavailability, first pass effect, systemic toxicity, degradation of drug in stomach...

Niosomes as Carrier in Dermal Drug Delivery

Niosomes: A Novel Drug Delivery System

Paul Ehrlich, in 1909, initiated the development for targeted delivery when he envisaged a drug delivery mechanism that would target directly to diseased cell. Drug targeting can be defined as the ability to direct a therapeutic agent specifically to desired site of action with little or no interaction with non target tissue 1 . In noisome, the vesicles forming amphiphile is a non-ionic surfact...

Vincristine loaded niosomes as an effective drug delivery system for lymphoma

  Aim and Background: Vincristine is a herbal anticancer drug which is used to treat a wide range of cancers such as lymphoma. Niosomes are important drug carriers. The aim of this study was to prepare PEGylated niosomal form of vincristine in order to increase its efficacy in lymph nodes’ cancer. Material and Methods: PEGylated niosomal vincristine (PEG-nVCR) was prepared by thin film hydrat...

Novel transdermal drug delivery systems

Background and aim: Eczema is a common inflammatory skin disease. Although history and physical examination are important in diagnosis of allergen, because of extent of environmental allergens, those are not simply recognized. The objective of this study was to determine allergens in patients with contact or atopic dermatitis referred to Razi hospital.Materials and Meth...